Die zweitägige Veranstaltung findet in Lugano, in englischer Sprache statt. Sie richtet sich hauptsächlich an Ärzte. Patienten- und Selbsthilfevertreter sind jedoch willkommen und können kostenfrei teilnehmen. Am ersten Tag findet morgens eine Session für Patientenvertreter statt (ebenfalls in englischer Sprache). Ob auch eine digitale Teilnahme möglich ist, ist derzeit noch nicht bekannt.

Zeit:
21. bis 22. September 2023

Ort:
USI Università della Svizzera Italiana
Aula Magna,
Lugano, Schweiz

Programm:

21. September 2023

09:00 – 10:30 Patients› session

• Pregnancy – Michael Heneghan
• Drug side effects – Maria Isabel Lucena and Raul Andrade
• New therapies – Michael Manns

Invited:

• SwissHePa
• UK PBC Foundation
• AMAF – TBC
• Deutsche Leberhilfe
• British Liver Trust – TBC
• Globalliver

11:00 – 11:15 Welcome Benedetta Terziroli Beretta-Piccoli and Andrea De
Gottardi
Welcome from Università della Svizzera Italiana – Giovanni
Pedrazzini

Basic science sessions

11:15 – 12:55 1. Genetics – Chairs: Gideon Hirschfield and Federica Sallusto
11:15 – 11:35 Genetics of PBC – Pietro Invernizzi
11:35 – 11:55 Genetics of PSC – Tom Karlsen
11:55 – 12:15 Genetics of AIH – Ynto de Boer
12:15 – 12:35 Inherited immune deficiencies and autoimmunity – Mike
Recher
12:35 – 12:55 Discussion

12:55 – 13:45 Lunch

13:45-16:40 2. Hot topics in autoimmune liver diseases – Chairs: Michael
Manns and Michael Trauner
13:45 – 14:05 Cellular therapies – Maria Serena Longhi
14:05 – 14:25 SARS-CoV-2 and liver autoimmunity – Gideon Hirschfield
14:25 – 14:45 Pregnancy in autoimmune liver diseases patients – Michael
Heneghan
14:45 – 15:05 Drug-induced AIH-like DILI – Maribel Lucena
15:05 – 15:25 Discussion

15:25 – 16:00 Coffee break

16:00 – 17:00 3. Oral presentations – Chairs: Michael Heneghan and
Giorgina Mieli-Vergani
16:00 – 16:15 Oral presentation 1
16:15 – 16:30 Oral presentation 2
16:30 – 16:45 Oral presentation 3
16:45 – 17:00 Oral presentation 4

17:00-18:20 4. Mechanisms of autoimmunity – Chairs: Diego Vergani and
Andreas Cerny
17:00 – 17:20 The Long and Latent Road to Autoimmunity – Eric Gershwin
17:20 – 17:40 T cells in autoimmunity – Federica Sallusto
17:40 – 18:00 Viruses and autoimmunity – Christian Münz
18:00 – 18:20 Discussion

18:20 – End of first day

22. September 2023

Clinical session

08:30 – 10:00 1. Diagonostic dilemmas – Chairs: Andrea De Gottardi and Andreas Kremer
08:30 – 08:45 Radiological clinical case presentation: the diagnosis of PSC
– Stefano Cappio and his fellow
08:45 – 09:05 Imaging in PSC and ASC – Annamaria Deganello
09:05 – 09:20 Serological case presentation: the diagnosis of AIH – Eric
Dayer and Benedetta Terziroli Beretta-Piccoli
09:20 – 09:40 Are autoantibodies still useful in the AI era? – Diego Vergani
09:40 – 10:00 Discussion

10:00 – 10:30 Coffee break

10:30 – 11:50 2. Treatment – Chairs: Andreas Kremer and Raul Andrade
10:30 – 10:50 Novel therapeutic targets for autoimmune cholestatic liver
diseases – Michael Trauner
10:50 – 11:10 Treatment of cholestatic pruritus – Andreas Kremer
11:10 – 11:30 Difficult to treat AIH patients – Ansgar Lohse
11:30 – 11:50 Discussion

11:50 – 12:50 Oral presentations – Chairs: Benedetta Terziroli Beretta-Piccoli
and Pietro Invernizzi
11:50 – 12:05 Oral presentation 1
12:05 – 12:20 Oral presentation 2
12:20 – 12:35 Oral presentation 3
12:35 – 12:50 Oral presentation 4

12:50-13:50 Lunch

13:50- 14:50 3. Pediatrics – Chairs: Giorgina Mieli-Vergani and Gideon
Hirschfield
13:50 – 14:05 Case presentation – Christiane Sokollik
14:05 – 14:25 Sclerosing cholangitis in pediatric IBD patients – Patrick van
Rheenen
14:25 – 14:45 Growing up with autoimmune liver disease: longterm
outcome of autoimmune liver disease – Marianne Samyn
14:45 – 15:05 Discussion

15:05 – 15:30 Coffee break

15:30 – 17:00 4. Checkpoint-inhibitors and the liver – Ansgar Lohse and
Maria Isabel Lucena
15:30 – 15:45 Clinical case presentation – Antonio Galante
15:45 – 16:05 Checkpoint-inhibitors-induced liver injury – Eleonora de
Martin
16:05 – 16:25 Liver histology of checkpoint-inhibitors-induced liver injury
– Yoh Zen
16:25 – 16:45 Can checkpoint inhibitors be used in patients with
autoimmune liver diseases? – Michael Manns
16:45 – 17:00 Discussion

17:00 – 17:20 Concluding remarques
Benedetta Terziroli Beretta-Piccoli
Andreas Kremer
Carina Bobzin
Robert Mitchell-Thain

17:20 End of the 4th Swiss AILD Meeting

Scientific committee:
Benedetta Terziroli Beretta-Piccoli – Chair
Andrea Cerny
Andrea De Gottardi
Diego Vergani
Giorgina Mieli-Vergani
Andreas Kremer

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